Tuscumbia is a city in and the county seat of Colbert County, Alabama.
Tuscumbia was the hometown of Helen Keller and is the location of the Alabama Music Hall of Fame.
The Tuscumbia known today had its beginnings when the Michael Dixon family arrived about 1816. They traded with Chief Tucumseh for the Tuscumbia Valley and built their home at the head of the big spring. From these humble dwellings quickly developed a village known as the Big Spring Community. The men of the community requested that the state legislatrue incorporate them as a city.
The town was incorporated in 1820 as Ococoposa and is one of Alabama's oldest towns. In 1821, its name was changed to Big Spring and on December 22, 1822 to Tuscumbia after the Chief Rainmaker of the Chickasaws.
Source: Wikipedia