Jonesborough was founded in 1779, 17 years before Tennessee became a state. It was named after North Carolina legislator, Willie Jones, who supported North Carolina's westward expansion over the Appalachian Mountains.
The town was originally a part of North Carolina. In 1784, Jonesborough was one of the towns that attempted to create a new state called the State of Franklin, named after American founding father Benjamin Franklin. The State of Franklin, however, was never recognized by Congress, and was re-claimed by North Carolina by 1788.